Real-time Monitoring and Control of Bioprocess UF/DF via In-line Tunable NIR Spectroscopy

In this poster from BPI BioTech Week 2025, the Atlas system enables real-time monitoring and control of UF/DF operations using advanced NIR spectroscopy (NIR-HPTLS). Unlike Raman methods that require intensive model development, Atlas delivers rapid quantification of proteins and excipients with simple implementation. By combining transferrable spectra libraries with robust process analytical technology (PAT), Atlas accelerates UF/DF optimization, reduces development time from months to hours, and supports automation in downstream bioprocessing.