NIR Reinvented

Our patented approach to NIR has been optimized to deliver on-demand access to critical analytical insights throughout the bioprocess.  Dubbed High-precision tunable laser spectroscopy (HPTLS), our core platform technology offers high-speed, ultra-stable performance for truly quantitative results of complex samples.


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Wide Tuning

Wide tuning range captures all relevant chemical signatures


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Repeatability

Wavelength and amplitude referencing yields incredible repeatability


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Accuracy

Accurate quantitive information from complex liquid samples

Our HPTLS technology harnesses the power of near-infrared (NIR) spectroscopy with the cutting-edge advancements of a tunable laser source to provide an elegant, quantitative method with wide dynamic range, accuracy and precision.


Bryan Hassell

Founder and CTO

Equipped with the power of HPTLS, Atlas can access bioprocess-relevant chemical signatures and produce quantitative results based on the signal-to-noise

Still Skeptical?

By repeating scans of water samples, it is shown that with HPTLS, you can achieve micro-absorbance repeatability.

The Power of NIR

Near-infrared (NIR) spectroscopy has been a vital process monitoring technology for many industries including oil and gas, food and beverage, chemicals, and pharmaceuticals. Its wealth of chemical information and robust signatures make it an ideal tool for quantifying complex compositions.

The NIR region contains a massive wealth of chemical information

The Near-Infrared (NIR) spectroscopic region provides a wealth of chemical information by capturing overtones and combinations of fundamental molecular vibrations. This technique enables the analysis of various organic compounds and materials, offering insights into molecular structure, composition, and interactions without the need for extensive sample preparation.


Source: https://www.nirlab.com/blog/nir-spectroscopy-nutshell/

So why hasn’t NIR been more widely adopted in biopharmaceuticals?

It’s because the majority of biopharmaceuticals are manufactured as liquid formulations, meaning they contain a lot of water. NIR wavelength light absorbs water orders of magnitude stronger than the UV-Visible spectrum, thus making the observable signal orders of magnitude smaller!


Water Data Adopted From: G. M. Hale and M. R. Querry, “Optical constants of water in the 200nm to 200-micron wavelength region,” Appl. Opt., 12, 555–563, (1973). Absorbance data for illustrative purposes only

Have Any Questions?

We’d love to talk with you about your needs in upstream process monitoring! Feel free to reach out to us and our helpful team will get back to you.

Atlas Reveals Blind Spots Throughout the Bioprocess

Atlas provides confident quantitative results for excipients and antibody titer concentrations 5000X faster; with 100X less sample and 10X cheaper than current techniques.


info@nirrin.tech

(781) 285-5450

44 Manning Road
Billerica, MA 01821

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