New product announcement — protein measurement made simple. Meet TALOS

High-Precision Tunable Laser Spectroscopy (HPTLS™)

Measurements, not predictions.

Direct quantitation built on precision tunable lasers, fixed-path optics, and full-spectrum spectral decomposition.

100× power density
1 mm fixed pathlength
~20 µAU repeatability
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A precision laser built for small spectral differences

HPTLS™ concentrates optical power where the chemistry is informative, rather than spreading light across a broad spectrum. That higher power density, combined with wavelength referencing and repeatable sweep control, makes weak spectral bands more measurable in complex aqueous samples.

100×
power density
0.01 nm
sweep resolution
4 Hz
sweep rate
HPTLS signal compared with a broad-band FT-NIR source: concentrated optical power in the informative spectral region.

The measurement geometry is part of the technology

A fixed ~1 mm pathlength keeps combination-band NIR in a controlled signal-to-noise regime. Because the geometry is specified rather than adjusted on the fly, the same quantitation logic can transfer across at-line, in-line, and in-situ measurements.

One pathlength discipline across interfaces

At-line

Discrete sample measurement

In-line

Flow-cell measurement

In-situ

Probe-based measurement

Known-component quantitation, not black-box calibration

Our model is a physically constrained Beer–Lambert fit. Known analytes and known background terms are represented explicitly in the spectrum, producing concentrations and a residual you can inspect. The result is quantitation tied to the sample, not hidden latent factors from a historical training set.

Known componentsBackground terms includedFull-spectrum fitReduced PLS burden
Known-component spectral model: analyte and background basis terms, full-spectrum fit, and quantified concentrations with residual.
Go deeper

Technology resources

App notes, downloads, and supporting documentation — or reach out to walk through the measurement model with our team.

See it in action

See HPTLS Working in Your Process

At your bench, in your process line, or in your vessel.